Gleason grading after neoadjuvant hormonal therapy retains prognostic value for systemic progression following radical prostatectomy
نویسندگان
چکیده
منابع مشابه
Racial differences in prognostic value of adult height for biochemical progression following radical prostatectomy.
PURPOSE Adult height, as a surrogate of childhood and adolescent hormone activity and diet, has been associated with the risk for development and death from prostate cancer in predominantly White populations. However, hormonal activity and diets vary between races. We examined whether height was significantly associated with biochemical progression following radical prostatectomy and whether th...
متن کاملPrognostic stratification in patients who received hormonal therapy for prostate-specific antigen recurrence after radical prostatectomy.
The present study was undertaken to investigate the predictors in patients who received hormonal therapy (HT) for prostate-specific antigen recurrence (PSAR) after surgery. Predictors for the progression-free survival were assessed in 55 patients who received HT for PSAR after surgery. In multivariate analysis, primary Gleason grade > or =4 and PSA doubling time (PSA-DT) <6 months were independ...
متن کاملNeoadjuvant hormonal deprivation for patients undergoing radical prostatectomy.
The purpose of this study is to evaluate the therapeutic effect of radical prostatectomy combined with preoperative neoadjuvant hormonal ablation therapy for prostate cancer (PCa). In this study, a total of 31 patients with local PCa underwent radical prostatectomy; of these, 12 patients underwent preoperative hormonal deprivation with a combination of goserelin and flutamide for a period of 5....
متن کاملNatural history of progression after PSA elevation following radical prostatectomy.
CONTEXT In men who develop an elevated serum prostate-specific antigen level (PSA) after having undergone a radical prostatectomy, the natural history of progression to distant metastases and death due to prostate cancer is unknown. OBJECTIVE To characterize the time course of disease progression in men with biochemical recurrence after radical prostatectomy. DESIGN A retrospective review o...
متن کاملGleason score as predictor of clinicopathologic findings and biochemical (PSA) progression following radical prostatectomy.
OBJECTIVE There is evidence showing that Gleason grading of prostatic adenocarcinoma is one of the most powerful predictors of biological behavior and one of the most influential factors used to determine treatment for prostate cancer. The aim of the current study was to compare the Gleason score for needle biopsy to the Gleason score for the correspondent surgical specimen, find any possible d...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Prostate Cancer and Prostatic Diseases
سال: 2014
ISSN: 1365-7852,1476-5608
DOI: 10.1038/pcan.2014.30